The Engel Group at The University of Chicago

The Engel Group strives to exploit femtosecond dynamics to steer and to control excited state reactivity. We use a combination of ultrafast spectroscopy, theory, synthesis, and biophysics to approach this problem.


 

Revealing Nature's Designs

Nature has had 2.4 billion years to evolve and engineer excited state dynamics. From photosynthesis to vision to photoenzymes, we examine natural mechanisms to steer excited states. Our goal is to isolate and identify new design principles to control quantum dynamics.

Steering Excited State Dynamics

Electronic excited states carry enough energy to make and break chemical bonds. Photochemistry operates outside the Born-Oppenheimer regime -- thereby escaping our standard chemical intuition. We seek new strategies to steer excited states and to control their reactivity.

 

Seeing the Unseen

You can't engineer what you can't see. We build new spectroscopic tools to probe femtosecond dynamics of electronic excitations. In living cells, protein complexes, and small molecules, we capture how these systems evolve with unprecedented depth and specificity.

Paper Accepted   3/1/2025

Coco LiHugh CairneySiddhartha SohoniLawson Lloyd

Congratulations to Coco Li, Hugh Cairney, Sid Sohoni, Lawson Lloyd, and our collaborators in the Galli and Schaller groups on having their paper entitled, "Connectivity-dependent Exciton-phonon Coupling in Cesium Bismuth Halide Quantum Dot" accepted to ACS Nano

Congratulations   2/17/2025

Pete Dahlberg

Congratulations to Pete Dahlberg, who has started a tenture-track position as an Assistant Professor in SLAC's Department of Photon Science and Stanford's Department of Structural Biology.

Paper Published   12/13/2024

Indranil GhoshQijie ShenPing-Jui

Congratulations to Indranil Ghosh, Qijie Shen, and Eric Wu on having their paper entitled, "Vibronic Conical Intersection Trajectory Signatures in Wave Packet Coherences" published in JPCL.

Congratulations   11/6/2024

Felice Chan

Congratulations to Felice Chan on receiving a Quad Grant to support her research in the laboratory.

Quantum Biology activities within the Engel Group

Quantum Biology

Ultrafast Spectroscopy activities within the Engel Group

Ultrafast Spectroscopy

Quantum Materials activities within the Engel Group

Quantum Materials

Photocatalysis activities within the Engel Group

Photocatalysis

Theory activities within the Engel Group

Theory

Coherent Dynamics activities within the Engel Group

Coherent Dynamics

Light Harvesting Materials activities within the Engel Group

Light Harvesting Materials

Ultrafast Chiral Response activities within the Engel Group

Ultrafast Chiral Response

Live Cell Studies activities within the Engel Group

Live Cell Studies

B.C. Li, H. Cairney, Y. Jin, J. Park, S. Sohoni, L.T. Lloyd, Y.Liu, J.E. Jureller, Y.J. Ryu, S. Chariton, V.B. Prakapenka, R.D. Schaller, G. Galli, and G.S. Engel, "Connectivity-dependent Exciton-phonon Coupling in Cesium Bismuth Halide Quantum Dots", ACS Nano 19, 10359–10368 (2025)

S. Sohoni,* P.-J. Wu,* Q. Shen, L.T. Lloyd, C. Macgregor-Chatwin, A. Hitchcock, and G.S. Engel, "Resonant Vibrational Enhancement of Downhill Energy Transfer in the C-Phycocyanin Chromophore Dimer", JPCL 15, 11569–11576 2024

* These authors contributed equally

University of Chicago
Chemistry Department
Biophysical Sciences
Institute for Molecular Engineering
James Franck Institute
Institute for Biophysical Dynamics
MRSEC
College
quantum
spectroscopy
materials
AFOSR
DARPA
Dreyfus
Searle
Keck
DTRA
Lockheed Martin
UChicago
NSSEFF
NSF
NIH
QNRF
DOE
Sloan